Effectiveness of treatment of iron-deficiency anemia in infants and young children with ferrous bis-glycinate chelate
- PMID: 11377130
- DOI: 10.1016/s0899-9007(01)00519-6
Effectiveness of treatment of iron-deficiency anemia in infants and young children with ferrous bis-glycinate chelate
Abstract
Forty infants, 6 to 36 mo old, with iron-deficiency anemia (hemoglobin < 11 g/dL) were matched and assigned to two groups. One group received FeS0(4) and the other received ferrous bis-glycinate chelate at a dose of 5 mg of Fe daily per kilogram of body weight for 28 d. Both groups had significant hemoglobin increases (P < 0.001), but only the group treated with ferrous bis-glycinate chelate had significant increases (P < 0.005) in plasma ferritin. Apparent iron bioavailabilities were calculated at 26.7% for FeS0(4) and 90.9% for ferrous bis-glycinate chelate. Regression analysis indicated that absorption of both sources of iron were similarly regulated by the body according to changes in hemoglobin. We concluded that ferrous bis-glycinate chelate is the iron of choice for the treatment of infants with iron-deficiency anemia because of its high bioavailability and good regulation.
Similar articles
-
Comparison of ferrous sulfate and ferrous glycinate chelate for the treatment of iron deficiency anemia in gastrectomized patients.Nutrition. 2008 Jul-Aug;24(7-8):663-8. doi: 10.1016/j.nut.2008.03.017. Epub 2008 May 21. Nutrition. 2008. PMID: 18499399 Clinical Trial.
-
The use of sweet rolls fortified with iron bis-glycinate chelate in the prevention of iron deficiency anemia in preschool children.Arch Latinoam Nutr. 2001 Mar;51(1 Suppl 1):48-53. Arch Latinoam Nutr. 2001. PMID: 11688082 Clinical Trial.
-
The use of sugar fortified with iron tris-glycinate chelate in the prevention of iron deficiency anemia in preschool children.Arch Latinoam Nutr. 2001 Mar;51(1 Suppl 1):54-9. Arch Latinoam Nutr. 2001. PMID: 11688083 Clinical Trial.
-
The chemistry of ferrous bis-glycinate chelate.Arch Latinoam Nutr. 2001 Mar;51(1 Suppl 1):7-12. Arch Latinoam Nutr. 2001. PMID: 11688084 Review.
-
Iron amino acid chelates.Int J Vitam Nutr Res. 2004 Nov;74(6):435-43. doi: 10.1024/0300-9831.74.6.435. Int J Vitam Nutr Res. 2004. PMID: 15743019 Review.
Cited by
-
New Insights into Iron Deficiency Anemia in Children: A Practical Review.Metabolites. 2022 Mar 25;12(4):289. doi: 10.3390/metabo12040289. Metabolites. 2022. PMID: 35448476 Free PMC article. Review.
-
Micronutrients Dietary Supplementation Advices for Celiac Patients on Long-Term Gluten-Free Diet with Good Compliance: A Review.Medicina (Kaunas). 2019 Jul 3;55(7):337. doi: 10.3390/medicina55070337. Medicina (Kaunas). 2019. PMID: 31277328 Free PMC article. Review.
-
Effects of inorganic trace minerals replaced by complexed glycinates on reproductive performance, blood profiles, and antioxidant status in broiler breeders.Poult Sci. 2020 May;99(5):2718-2726. doi: 10.1016/j.psj.2019.11.058. Epub 2020 Mar 26. Poult Sci. 2020. PMID: 32359609 Free PMC article.
-
Effect of supplementation with ferrous sulfate or iron bis-glycinate chelate on ferritin concentration in Mexican schoolchildren: a randomized controlled trial.Nutr J. 2014 Jul 15;13:71. doi: 10.1186/1475-2891-13-71. Nutr J. 2014. PMID: 25023784 Free PMC article. Clinical Trial.
-
Postnatal Iron Supplementation with Ferrous Sulfate vs. Ferrous Bis-Glycinate Chelate: Effects on Iron Metabolism, Growth, and Central Nervous System Development in Sprague Dawley Rat Pups.Nutrients. 2021 Apr 22;13(5):1406. doi: 10.3390/nu13051406. Nutrients. 2021. PMID: 33921980 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous
