Effectiveness of treatment of iron-deficiency anemia in infants and young children with ferrous bis-glycinate chelate
- PMID: 11377130
- DOI: 10.1016/s0899-9007(01)00519-6
Effectiveness of treatment of iron-deficiency anemia in infants and young children with ferrous bis-glycinate chelate
Abstract
Forty infants, 6 to 36 mo old, with iron-deficiency anemia (hemoglobin < 11 g/dL) were matched and assigned to two groups. One group received FeS0(4) and the other received ferrous bis-glycinate chelate at a dose of 5 mg of Fe daily per kilogram of body weight for 28 d. Both groups had significant hemoglobin increases (P < 0.001), but only the group treated with ferrous bis-glycinate chelate had significant increases (P < 0.005) in plasma ferritin. Apparent iron bioavailabilities were calculated at 26.7% for FeS0(4) and 90.9% for ferrous bis-glycinate chelate. Regression analysis indicated that absorption of both sources of iron were similarly regulated by the body according to changes in hemoglobin. We concluded that ferrous bis-glycinate chelate is the iron of choice for the treatment of infants with iron-deficiency anemia because of its high bioavailability and good regulation.
Similar articles
-
Comparison of ferrous sulfate and ferrous glycinate chelate for the treatment of iron deficiency anemia in gastrectomized patients.Nutrition. 2008 Jul-Aug;24(7-8):663-8. doi: 10.1016/j.nut.2008.03.017. Epub 2008 May 21. Nutrition. 2008. PMID: 18499399 Clinical Trial.
-
The use of sweet rolls fortified with iron bis-glycinate chelate in the prevention of iron deficiency anemia in preschool children.Arch Latinoam Nutr. 2001 Mar;51(1 Suppl 1):48-53. Arch Latinoam Nutr. 2001. PMID: 11688082 Clinical Trial.
-
The use of sugar fortified with iron tris-glycinate chelate in the prevention of iron deficiency anemia in preschool children.Arch Latinoam Nutr. 2001 Mar;51(1 Suppl 1):54-9. Arch Latinoam Nutr. 2001. PMID: 11688083 Clinical Trial.
-
The chemistry of ferrous bis-glycinate chelate.Arch Latinoam Nutr. 2001 Mar;51(1 Suppl 1):7-12. Arch Latinoam Nutr. 2001. PMID: 11688084 Review.
-
Iron amino acid chelates.Int J Vitam Nutr Res. 2004 Nov;74(6):435-43. doi: 10.1024/0300-9831.74.6.435. Int J Vitam Nutr Res. 2004. PMID: 15743019 Review.
Cited by
-
Adherence to UNRWA's anaemia treatment guidelines in the Jerash Camp Health Centre, Jordan: a retrospective observational study.BMJ Open. 2022 Mar 1;12(3):e056490. doi: 10.1136/bmjopen-2021-056490. BMJ Open. 2022. PMID: 35232788 Free PMC article.
-
Iron deficiency anemia among kindergarten children living in the marginalized areas of Gaza Strip, Palestine.Rev Bras Hematol Hemoter. 2014 Mar;36(2):132-8. doi: 10.5581/1516-8484.20140030. Rev Bras Hematol Hemoter. 2014. PMID: 24790539 Free PMC article.
-
Postnatal Iron Supplementation with Ferrous Sulfate vs. Ferrous Bis-Glycinate Chelate: Effects on Iron Metabolism, Growth, and Central Nervous System Development in Sprague Dawley Rat Pups.Nutrients. 2021 Apr 22;13(5):1406. doi: 10.3390/nu13051406. Nutrients. 2021. PMID: 33921980 Free PMC article.
-
Ferrus calcium citrate is absorbed better than iron bisglycinate in patients with Crohn's disease, but not in healthy controls.Dig Dis Sci. 2006 May;51(5):942-5. doi: 10.1007/s10620-005-9036-6. Epub 2006 Apr 27. Dig Dis Sci. 2006. PMID: 16642425
-
Iron Bioavailability from Infant Cereals Containing Whole Grains and Pulses: A Stable Isotope Study in Malawian Children.J Nutr. 2022 Mar 3;152(3):826-834. doi: 10.1093/jn/nxab406. J Nutr. 2022. PMID: 34958374 Free PMC article. Clinical Trial.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous
